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GENATLAS PHENOTYPE

last update : 10-04-2018

Symbol	PPCD4
Location	8q22.3
Name	posterior polymorphous corneal dystrophy 4
Corresponding gene	GRHL2
Main clinical features	disorder, primarily affecting the corneal endothelium and Descemet membrane mild manifestations of the disease include asymptomatic corneal endothelial changes such as vesicular, band-like, and geographic lesions; in severe cases, corneal endothelial failure may occur and corneal transplantation is required to restore vision
Genetic determination	autosomal dominant
Function/system disorder	eye
Type	disease

Remark(s)