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GENATLAS PHENOTYPE

last update : 08-11-2017

Symbol	PARK21
Location	3q22.1
Name	Parkinson disease 21
Corresponding gene	DNAJC13
Main clinical features	typical adult-onset Parkinson disease characterized by tremor, rigidity, bradykinesia, postural instability, and good response to levodopa treatment postmortem examination of 3 affected individuals showed loss of dopaminergic neurons and Lewy bodies and Lewy neurites in the substantia nigra
Genetic determination	autosomal dominant
Related entries	including also cases of essential tremor (PMID: 25118025)
Function/system disorder	neurology
Type	disease

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