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Orphanet References OMIM Gene GeneReviews HGMD HGNC
last update : 5/09/2006
Symbol P2RY12
Location 3q24-q25
Name platelet ADP receptor defect
Other name(s) bleeding disorder due to P2RY12 defect
Corresponding gene P2RY12
Main clinical features
  • bleeding disorder linked to a defective interaction between ADP (adenine diphosphate) and its receptor on platelets and a secundary defect of GP2B/GPRA function, with reduced capacity of platelets to bind to each other in response to ADP
  • Genetic determination
    Function/system disorder hematology
    Type disease
    Gene product
    Name purinoreceptor P2Y12