Home Page

References

OMIM

Gene

GeneReviews

HGMD

HGNC

GENATLAS PHENOTYPE

last update : 02/02/08

Symbol	OHSS
Location	2p21-p16
Name	ovarian hyperstimulation syndrome
Main clinical features	vary from abdominal distention and discomfort to potentially life-threatening, massive ovarian enlargement and capillary leak with fluid sequestration . chorionic gonadotropin (hCG) promiscuously stimulates the FSHR during the first trimester of pregnancy
Genetic determination	not applicable
Function/system disorder
Type	disease

Remark(s)

mutations only in the transmembrane helices of the serpentine region of the FSHR, outside the hormone binding domain