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GENATLAS PHENOTYPE

last update : 18-12-2013

Symbol	NPHS8
Location	17q25.3
Name	nephrotic syndrome, type 8
Other name(s)	in the first weeks of life, severe proteinuria, hypoalbuminemia, and generalized edema renal biopsy showed diffuse mesangial sclerosis, with small glomeruli, hypercellularity, increased extracellular matrix, electron microscopy showed diffuse effacement of foot processes, thinning of the glomerular basement membrane, and swollen endothelial cells
Corresponding gene	ARHGDIA
Genetic determination	autosomal recessive
Function/system disorder	kidney and urinary tract
Type	disease

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