Symbol
| NPHS7
|
Location
| 17q22
|
Name
|
nephrotic syndrome, type 7 |
Corresponding gene
|
DGKE
|
Main clinical features
|
onset of nephrotic syndrome with proteinuria usually in the first decade of life; the disorder is progressive, and some patients develop end-stage renal disease within several years
renal biopsy typically shows membranoproliferative glomerulonephritis |
Genetic determination
| autosomal recessive |
Related entries
| including atypical hemolytic uremic syndrome-7 (AHUS7), characterized by acute onset in the first year of life of microangiopathic hemolytic anemia, thrombocytopenia, and renal failure
|
Function/system disorder
| kidney and urinary tract |
Type
| disease
|