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GENATLAS PHENOTYPE
last update : 25-02-2009
Symbol NNHA
Location 11q23.3
Name non neuropathic hereditary systemic amyloidosis
Other name(s) amyloidosis familial visceral
Corresponding gene APOA1
Other symbol(s) FAR3
Main clinical features
  • widely deposition of amyloid and a great clinical variation among and between families with major clinical problems related to renal, hepatic or cardiac involvement (APOA1 defect with a single extrapositive charge)
  • Genetic determination autosomal dominant
    Function/system disorder cardiovascular
    kidney and urinary tract
    digestive tract/liver and annex
    Type disease
    Gene product
    Name apoliprotein A1 (APOA1)
    Remark(s)