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GENATLAS PHENOTYPE |
last update : 03-11-2010 |
Symbol | MCPCM |
Location | 19q13.12 |
Name | microcephaly with cortical malformations |
Corresponding gene | WDR62 |
Main clinical features |
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Genetic determination | autosomal recessive |
Function/system disorder | neurology |
Type | disease |
Remark(s) | . a proliferative defect in brains of individuals with WDR62 mutations, potentially affecting the outer SVZ (precursors to upper layer cortical neurons) as well as defective neuronal migration |