| Symbol
| LVNC8
|
| Location
| 1p36.32
|
| Name
|
left ventricular noncompaction cardiomyopathy 8 |
| Other name(s)
|
cardiomyopathy, dilated, 1LL |
| Corresponding gene
|
PRDM16
|
| Other symbol(s)
| CMD1LL
|
| Main clinical features
|
left ventricular noncompaction is characterized by numerous prominent trabeculations and deep intertrabecular recesses in hypertrophied and hypokinetic segments of the left ventricle
heart failure with systolic and diastolic dysfunction, secondary pulmonary hypertension, and dilation of both atria and ventricles; echocardiography showed involvement of apical and lateral segments, with marked thickening of the inferior noncompacted layer below the left ventricular papillary muscles and thinning of the compacted layer |
| Genetic determination
| autosomal dominant |
| Related entries
| including CMD1LL,Cardiomyopathy, dilated, 1LL
|
| Function/system disorder
| cardiovascular |
| Type
| disease
|