| Symbol
| LPAC
|
| Location
| 7q21.12
|
| Name
|
low phospholipid-associated cholelithiasis |
| Other name(s)
|
gallbladder disease-1 |
| Corresponding gene
|
ABCB4
|
| Other symbol(s)
| GBD1
|
| Main clinical features
|
specific form of gallbladder disease characterized by young-adult onset of chronic cholestasis with intrahepatic sludge and cholesterol cholelithiasis
recurrence of the disorder after cholecystectomy and favorable response to treatment with ursodeoxycholic acid |
| Genetic determination
| multigenic |
| Function/system disorder
| digestive tract/liver and annex |
| Type
| disease
|