Symbol
| IPEX
|
Location
| Xp11.23
|
Name
|
immunodysregulation, polyendocrinopathy, enteropathy |
Other name(s)
|
X-linked autoimmunity-allergic dysregulation syndrome
. IDDM-secretory diarrhea syndrome
. autoimmunity-immunodeficiency syndrome
. enteropathy, autoimmune, with hemolytic anemia and polyendocrinopathy
. diabetes mellitus, congenital insulin-dependent, with fatal secretory diarrhea |
Corresponding gene
|
FOXP3
|
Other symbol(s)
| XLAAD, DMSD, XPID
|
Main clinical features
|
autoimmune enteropathy with diarrhea, atopic dermatitis, immune deficiency and fatal infections |
Genetic determination
| sex linked |
Function/system disorder
| defense and immunity |
| digestive tract/gastrointestinal |
| endocrinology |
Type
| disease
|