| Main clinical features
|
type A, a syndrome of younger females with signs of virilization and accelerated growth in whom a defect in cell receptors for insulin may be primary
type B, in older females with signs of an immunologic disease in whom circulating antibodies to the insulin receptor
mild diabetes in combination with acanthosis nigricans and minor physical abnormalities: bitemporal narrowing of the skull, paucity of body fat, acral hypertrophy (enlarged ears, nose, chin, and finger tips), brachydactyly, protrusion of the eye globes, and dental anomalies |