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GENATLAS PHENOTYPE

last update : 06-09-2017

Symbol	IMD39
Location	11p15.5
Name	Immunodeficiency 39
Corresponding gene	IRF7
Main clinical features	life-threatening H1N1 influenza A infection, but no detectable immunologic abnormalities suggesting any T- or B-cell defects in response to influenza virus, the patient's leukocytes and plasmacytoid dendritic cells produced very little type I and III interferons (IFNs)
Genetic determination	autosomal recessive
Function/system disorder	defense and immunity
Type	disease

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