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References OMIM Gene GeneReviews HGMD HGNC
last update : 06-09-2017
Symbol IMD39
Location 11p15.5
Name Immunodeficiency 39
Corresponding gene IRF7
Main clinical features
  • life-threatening H1N1 influenza A infection, but no detectable immunologic abnormalities suggesting any T- or B-cell defects
  • in response to influenza virus, the patient's leukocytes and plasmacytoid dendritic cells produced very little type I and III interferons (IFNs)
  • Genetic determination autosomal recessive
    Function/system disorder defense and immunity
    Type disease