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GENATLAS PHENOTYPE

last update : 13/07/2006

Symbol	IDTF
Location	20p13
Name	insomnia-dysautonomia thalamic syndrome
Other name(s)	fatal familial insomnia
Corresponding gene	PRNP
Other symbol(s)	FFI
Main clinical features	associated with organic dementia, neuronal loss, also gliosis in the thalamus and spongiosis of the cortex (evolution linked to PRN polymorphism)
Genetic determination	autosomal dominant
Function/system disorder	neurology
	psychiatric disorder
Type	disease

Gene product

Name	prion protein (PRNP)

Remark(s)