| Symbol
| HUS2
|
| Location
| 6p21.3
|
| Name
|
hemolytic-uremic syndrome, atypical 2 |
| Corresponding gene
|
CFB
|
| Main clinical features
|
characterized by the simultaneous occurence of microangiopathic hemolytic anemia and acute renal insufficency that was not preceded by either a diarrheal prodrome or an enteric infection
. thrombocytopenia, Coomb's test-negative microangiopathic hemolytic anemia and acute renal failure |
| Genetic determination
| not applicable |
| Function/system disorder
| hematology |
|
| kidney and urinary tract |
| Type
| disease
|
| Gene mutation | Chromosome rearrangement | Effect | Comments |
|
|---|
| unknown
|
| abnormal protein/gain of function
|
| |