Main clinical features
|
developmental disorder characterized by complex congenital heart malformations and/or situs inversus and caused by defects in the normal left-right asymmetric positioning of internal organs
complex cardiac anomalies, variably including dextrocardia, transposition of the great arteries, atrial and/or ventricular septal defects, abnormal vessel draining, interruption of the vena cava drainage, and anomalous pulmonary venous return, associated to extracardiac laterality defects were also common but variable, and included situs inversus totalis, situs ambiguus, pulmonary isomerism, intestinal malrotation, midline liver, and polysplenia |