| Symbol
| HTX1
|
| Location
| Xq26.2
|
| Name
|
abnormal left-right axis with visceral heterotaxy (situs ambiguus), 1 |
| Other name(s)
|
dextrocardia with other cardiac malformations laterality, X-linked
situs inversus, complex cardiac defects and splenic defect |
| Corresponding gene
|
ZIC3
|
| Other symbol(s)
| HTX
|
| Main clinical features
|
cardiac and splenic defects, gastrointestinal malrotation cleft lip, defects of the lumbosacral spine (neural tube defect) and hind-gutwith an uncomplete penetrance among males
also expressed in heterozygous female (ZIC3 defect) |
| Genetic determination
| sex linked |
| Related entries
| . includes isolated d-transposition of the great arteries and double outlet right ventricle (PMID: 23427188)
|
| Function/system disorder
| congenital malformation |
| Type
| disease
|