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GENATLAS PHENOTYPE
last update : 7/07/2006
Symbol HLF
Location 17q22 and 19p13
Name acute lymphoblastic leukemia, preB-cell
Corresponding gene HLF , TCF3
Main clinical features
  • with t(17;19)(q22;p13) translocation (see TCF3),associated with CDNK2A and/or CDKN2B deletion
  • Genetic determination
    Function/system disorder hematology
    Type malignancy
    Gene product
    Name chimeric fusion protein 5'- TCF3/E2A - HLF -3'