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GENATLAS PHENOTYPE
last update : 25/08/2006
Symbol GTS13
Location 13q31.1
Name Tourette syndrome, chromosome 13 related
Other name(s) Gilles de la Tourette syndrome
Corresponding gene SLITRK1
Other symbol(s) OCD10
Main clinical features
  • complex neuropsychiatric disorder characterized by chronic vocal and motor tics
    • Genetic determination not applicable
    Related entries GTS18
    Function/system disorder psychiatry disorder
    Type disease
    Mechanism(s)
    Gene mutationChromosome rearrangementEffectComments
    frameshift   abnormal protein/loss of function one mutation identified
    Remark(s)
  • complex mode of inheritance likely involving contribution of several genes with different effect size
  • other localisations suggested by breakpoints or linkage includes 18q22 (see GTS18), 8p, 4q, 11q23, 8q22, 2p11, 7q31, 17q25, 9q24
  • a gene of major effect could be located on 2p32.2