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GENATLAS PHENOTYPE

last update : 11-07-2023

Symbol	FTA1
Location	4p16.2
Name	familial tooth agenesis, oligodontia 1
Other name(s)	hypodontia
Corresponding gene	MSX1
Other symbol(s)	HYD1, STHAG1
Main clinical features	involving predominantly maxillary and mandibular second premolars and third molars associated or not with orofacial clefting
Genetic determination	autosomal dominant
Related entries
Function/system disorder	osteo-articular
	dermatology
Type	disease

Gene product

Name	protein with a homeo domain (MSX1), inconsistent results

Mechanism(s)

Gene mutation	Chromosome rearrangement	Effect	Comments
missense		unknown	disruption of DNA binding or of protein stability

Remark(s)