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GENATLAS PHENOTYPE
last update : 21/05/2007
Symbol FL3B
Location 3q27.3
Name follicular lymphoma grade 3B
Corresponding gene BCL6
Main clinical features
  • 3q27 rearrangements are predominantly associated with follicular lymphoma grade 3B harboring a diffuse large B-cell component.
    • Genetic determination other
    Function/system disorder hematology
    Type malignancy
    Gene product
    Name chimeric fusion protein(s)
    Mechanism(s)
    Gene mutationChromosome rearrangementEffectComments
      translocation   acquired, present in tumor cells, various partners
    Remark(s) 3q27 rearrangements are predominantly associated with FL grade 3B harboring a DLBL component.