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GENATLAS PHENOTYPE

last update : 28-09-2011

Symbol	FHA3
Location	11q24.3
Name	hyperaldosteronism, familial, type III
Corresponding gene	KCNJ5
Main clinical features	characterized by hypertension secondary to massive adrenal mineralocorticoid production childhood hypertension, elevated aldosteronism levels, and high levels of the hybrid steroids 18-oxocortisol and 18-hydroxycortisol histology revealed massive hyperplasia and cellular hypertrophy of a single cortical compartment that had features of adrenal fasciculata or a transitional zone, with an atrophic glomerulosa
Genetic determination	autosomal dominant
Function/system disorder	endocrinology
Type	disease

Remark(s)