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References OMIM Gene GeneReviews HGMD HGNC
last update : 14-09-2016
Symbol FAP4
Location 5q14.1
Name familial adenomatous polyposis 4
Corresponding gene MSH3
Main clinical features . tumor predisposition syndrome characterized by the development of multiple colonic adenomas in adulthood, often with progression to colorectal cancer
  • precancerous conditions characterized by the presence of dozens to thousands of adenomatous polyps, which, unless detected early and removed, invariably result in colorectal cancer
  • Genetic determination autosomal recessive
    Function/system disorder digestive tract/liver and annex
    Type disease