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GENATLAS PHENOTYPE

last update : 14-09-2016

Symbol	FAP4
Location	5q14.1
Name	familial adenomatous polyposis 4
Corresponding gene	MSH3
Main clinical features	. tumor predisposition syndrome characterized by the development of multiple colonic adenomas in adulthood, often with progression to colorectal cancer precancerous conditions characterized by the presence of dozens to thousands of adenomatous polyps, which, unless detected early and removed, invariably result in colorectal cancer
Genetic determination	autosomal recessive
Function/system disorder	digestive tract/liver and annex
Type	disease

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