| Main clinical features
|
severe neurologic disorder characterized by onset of refractory migrating focal seizures in infancy, developmental regression and are severely impaired globally
focal seizures manifest as eye deviation, unresponsiveness, apnea, hemiclonic twitching, and tonic and atonic seizures; global developmental regression after onset of seizures, and the seizures were pharmacoresistant
EEG showed variable foci of epileptic activity as well as interictal diffuse slowing and multifocal spikes |