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GENATLAS PHENOTYPE

last update : 09-07-2023

Symbol	ECTD3
Location	4p16.2
Name	ectodermal dysplasia 3, Witkop type
Corresponding gene	MSX1
Main clinical features	ectodermal dysplasia involving the teeth and nails with sparse or fine hair, but also affected individuals have normal hair, sweat glands, and ability to tolerate heat nails are generally thin, slow-growing, brittle, and spoon-shaped (koilonychia); toenails are usually more severely affected than fingernails
Genetic determination	autosomal dominant
Function/system disorder	dermatology
Type	disease

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