| Main clinical features
|
triad of cutaneous findings including reticulate hyperpigmentation, noncicatricial alopecia, and onychodystrophy associated to variable features including adermatoglyphia, hypohidrosis or hyperhidrosis, and palmoplantar hyperkeratosis
reticulate pattern of skin hyperpigmentation, thickening of the palms and soles (palmoplantar keratoderma), abnormal sweating, and other subtle developmental anomalies of the teeth, hair, and skin with lifelong persistence of the skin hyperpigmentation, partial alopecia, and absence of dental anomalies |