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References OMIM Gene GeneReviews HGMD HGNC
last update : 21-01-2014
Symbol DDD3
Location 3q13.33
Name Dowling-Degos disease 3
Corresponding gene POGLUT1
Main clinical features
  • progressive and disfiguring reticulate hyperpigmentation
  • disseminated pattern of brownish macular and lentiginous lesions on the extremities, trunk/back and neck without the typical domination of the flexural folds observed in classical DDD
  • reticulate hyperpigmentation and hyperkeratotic brown papules on the back , breast , trunk , arm, and legs (PMID: 24387993))
  • Genetic determination autosomal dominant
    Function/system disorder dermatology
    Type disease