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GENATLAS PHENOTYPE

last update : 20-04-2010

Symbol	CYP2D6DM
Location	22q13.1
Name	drug metabolism, CYP2D6-related
Corresponding gene	CYP2D6
Main clinical features	poor and/or ultrarapid metabolism of several drugs, including debrisoquine, sparteine, nortriptyline, and codeine
Genetic determination	autosomal recessive
Function/system disorder	metabolism/pharmacogenetics
Type	other

Gene product

Name	cytochrome P450, subfamily IID (CYP2D6)

Remark(s)

putative susceptibility gene for ankylosing spondylitis and putative for leukemia