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References OMIM Gene GeneReviews HGMD HGNC
last update : 11-07-2017
Symbol CRMO2
Location 1p36.21
Name chronic recurrent multifocal osteomyelitis 2
Corresponding gene FBLIM1
Main clinical features
  • inflammation had both subacute and chronic features, with lesions located predominantly in the metaphyses of the long bones
  • autoinflammatory disease characterized by bone pain due to sterile osteomyelitis, and is often accompanied by psoriasis or inflammatory bowel disease
  • likely a disorder of chronic inflammation and imbalanced bone remodeling
  • Genetic determination not applicable
    Function/system disorder defense and immunity
    Type disease