Symbol
| CAN
|
Location
| 9q34.13 and 6p23
|
Name
|
myelodysplastic syndrome, refractory anemia |
Corresponding gene
|
NUP214
, DEK
|
Main clinical features
|
with excess of blasts in transformation (MDS/RAEBT), acute myeloid leukemia (AML), with t(6;9)(p23;q34) translocation |
Genetic determination
Function/system disorder
| hematology |
Type
| malignancy
| |
Name
| chimeric fusion protein (165kD) 5'- DEK - NUP214(CAN) -3'
|
Gene mutation | Chromosome rearrangement | Effect | Comments |
|
---|
 
| translocation
|  
| acquired t(6;9) associated with aspecific subtype of acute myeloid leukemia
| |