Home Page

References

OMIM

Gene

GeneReviews

HGMD

HGNC

GENATLAS PHENOTYPE

last update : 03-12-2020

Symbol	CADINS
Location	7p22.2
Name	CARD11-associated atopy with dominant interference of NFKB1 signaling
Other name(s)	immunodeficiency 11B with atopic dermatitis
Corresponding gene	CARD11
Other symbol(s)	IMD11B
Main clinical features	immune dysfunction characterized by onset of moderate to severe atopic dermatitis in early childhood some patients may have recurrent infections and other variable immune abnormalities laboratory studies show defects in T-cell activation, increased IgE, and eosinophilia
Genetic determination	autosomal dominant
Function/system disorder	defense and immunity
Type	disease

Remark(s)