| Main clinical features
|
hypokalemic metabolic acidosis and renal salt wasting, and a highly variable phenotype ranging from episodes of severe dehydratation in neonatal period to almost asymptomatic patients during adolescence
antenatal (or neonatal) forms of Bartter syndrome typically present with premature birth associated with polyhydramnios and low birth weight and may develop life-threatening dehydration in the neonatal period; classic Bartter syndrome present later in life and may be sporadically asymptomatic or mildly symptomatic |