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GENATLAS PHENOTYPE

last update : 12/06/2006

Symbol	BCL2
Location	18q21.33
Name	non Hodgkin follicular lymphoma of B-cell type
Corresponding gene	BCL2
related resource	MITOP database
Main clinical features	diffuse large B cell lymphoma, with translocation t(14;18)(q32;q21.3)
Genetic determination
Related entries	. extranodal B cell lymphoma (low grade lymphoma of mucosa associated lymphoid tissue), with translocation t(11;18)(q21;q21) and a breakpoint on chromosome 18 between BCL2 and DCC
Function/system disorder	hematology
Type	malignancy

Gene product

Name	chimeric fusion protein BCL2-IGH or BCL2 overexpression