Symbol
| ALSG
|
Location
| 5p12
|
Name
|
aplasia of lacrymal and salivary gland |
Other name(s)
|
lacrimo-auriculo-dento-digital syndrome |
Corresponding gene
|
FGF10
|
Other symbol(s)
| LADD
|
Main clinical features
|
irritable eyes, epiphora (constant tearing), and xerostomia (dryness of the mouth), which increases risk of dental erosion, dental caries, periodontal disease, and oral infections |
Genetic determination
| autosomal dominant |
Related entries
| including LADD, lacrimo-auriculo-dento-digital syndrome (MIM 149730), characterized by aplasia, atresia or hypoplasia of the lacrimal and salivary systems, cup-shaped ears, hearing loss, and dental and digital anomalies
|
Function/system disorder
| eye |
| digestive tract/gastrointestinal |
| osteo-articular |
Type
| malformation
|