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GENATLAS PHENOTYPE

last update : 26-06-2018

Symbol	ALS23
Location	10q22.3
Name	amytrophic lateral sclerosis 23
Corresponding gene	ANXA11
Main clinical features	neurodegenerative disorder characterized by the death of motor neurons in the brain, brainstem, and spinal cord, resulting in fatal paralysis. ALS usually begins with asymmetric involvement of the muscles in middle adult life late onset (range, 50 to 83 years; average, 67 years) of classic ALS disease symptoms without dementia
Genetic determination	autosomal dominant
Function/system disorder	neuromuscular
Type	disease

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