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GENATLAS PHENOTYPE

last update : 11-04-2012

Symbol	AINHL
Location	mt
Name	aminoglycoside-induced and nonsyndromic hearing loss
Corresponding gene	MT-ND4 , COX1
Main clinical features	severe permanent perceptive hearing loss developed during therapy with streptomycin and others aminoglycoside, bilateral hearing loss of high frequencies and symmetries
Genetic determination	autosomal dominant
Function/system disorder	ear
Type	disease

Remark(s)

homoplasmic 12S rRNA A1555G mutation of MTND4