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GENATLAS PHENOTYPE

last update : 01-10-2009

Symbol	AEZ
Location	8q24.3
Name	acrodermatitis enteropathica
Corresponding gene	SLC39A4
Main clinical features	diarrhea, alopecia, growth failure, zinc deficiency type periorificial and acral dermatitis, alopecia, and diarrhea, caused by a defective intestinal zinc absorption, especially in the duodenum and jejunum, two key sites for zinc homeostasis decrease in plasma and serum zinc levels (<50 mg/dL
Genetic determination
Function/system disorder	metabolism/metal
Type	disease

Gene product

Name	solute carrier family 39 member 4

Remark(s)