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References OMIM Gene GeneReviews HGMD HGNC
last update : 14-03-2018
Symbol ACNINV2
Location 19q13.12
Name acne inversa, familial, 2, with or without Dowling-Degos disease
Corresponding gene PSENEN
Main clinical features
  • chronic inflammatory disease of the hair follicles whose characteristic features include draining sinuses, painful skin abscesses, and disfiguring scars
  • manifestations typically appear after puberty
  • also associated with reticulate hyperpigmentation consistent with Dowling-Degos disease
  • Genetic determination autosomal dominant
    Function/system disorder dermatology
    Type disease