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References OMIM Gene GeneReviews HGMD HGNC
last update : 13/07/2006
Symbol IGAN1
Location 6q22-q23
Name IgA nephropathy
Other name(s) Berger disease
Main clinical features
  • most common form of glomerulonephritis . onset before the age of 40 years with hematuria and proteinuria and a progressive renal failure in 30 percent of patients . incomplete penetrance, heterogeneous
  • Genetic determination autosomal dominant
    Related entries IGAN2, IGAN3
    Function/system disorder kidney and urinary tract
    Type susceptibility factor
    Remark(s) evidence of linkage to multiple chromosomal regions was considered consistent with both an oligo/polygenic and a multiple susceptibility gene model for familial IGAN, with small or moderate effects in determining the pathologic phenotype.