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FLASH GENE
Symbol ZZEF1 contributors: KTN/npt - updated : 12-02-2009
HGNC name zinc finger, ZZ-type with EF hand domain 1
HGNC id 29027
Location 17p13.2      Physical location : 3.907.739 - 4.046.253
Synonym symbol(s) ZZZ4, KIAA0399, FLJ10821, FLJ23789, FLJ45574, MGC166929
DNA
TYPE functioning gene
STRUCTURE 138.52 kb     55 Exon(s)
MAPPING cloned Y linked N status confirmed
Map pter - D17S1583 - D17S1828 - ZZEF1 - D17S1584 - D17S1810 - cen
Authors UCSC (2009)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
55 - 11412 330.9 2961 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node    
 spleen    
 thymus    
Nervousbrainhindbraincerebellum lowly
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text stem cells
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a EF-hand calcium binding motif
  • a DOC domain
  • two ZZ-type zinc fingers
  • conjugated PhosphoP
    mono polymer complex
    HOMOLOGY
    interspecies homolog to rattus Zzef1 (91.2 pc)
    homolog to murine Zzef1 (91.3 pc)
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in regulation of mitotic metaphase/anaphase transition
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • anaphase-promoting complex
  • INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Zn2+
  • Ca2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS