Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ZNF644 contributors: mct - updated : 17-03-2014
HGNC name zinc finger protein 644
HGNC id 29222
Corresponding disease
MYP21 myopia 21
Location 1p22.2      Physical location : 91.380.859 - 91.487.671
Synonym name
  • zinc finger C2H2 type
  • zinc finger motif enhancer-binding protein 2
  • Synonym symbol(s) FLJ13964,dJ924G13.1, KIAA1221, BM-005, MGC70410, Zep-2, BM-005, MYP21, NatF, ZEP-2
    DNA
    TYPE functioning gene
    STRUCTURE 106.82 kb     6 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 2085 - 105 - 2011 21695231
    4 - 2004 - 105 - 2011 21695231
    6 - 5648 149 1327 - 2011 21695231
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Endocrinepancreas    
    Nervousbrain    
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    zinc finger C2H2 type
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in the transcription regulation, DNA dependent
  • transcription factor that may regulate genes involved in eye development
  • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
  • ZNF644 interact with the transcription activation domain of EHMT2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) MYP21
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS