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FLASH GENE
Symbol ZNF628 contributors: npt - updated : 29-01-2010
HGNC name zinc finger protein 628
HGNC id 28054
Location 19q13.42      Physical location : 55.987.698 - 55.995.854
Synonym name
  • zinc finger expressed in embryonal cells and certain adult organs
  • zinc finger protein Zec
    • Synonym symbol(s) MGC105139, ZEC, Zfp628
    DNA
    TYPE functioning gene
    STRUCTURE 8.16 kb     3 Exon(s)
    regulatory sequence Binding site
    text structure
  • ZEC binding DNA sequence,
  • C/GA/TA/TGGTTGGTTGC, the GT box not containing binding sites for other previously characterized transcription factors and thus represented a potentially novel DNA target sequence
    • MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 3867 - 1055 - Chen (2004)
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrinepancreas    
    Respiratorylung    
    Skin/Tegumentskin    
    Urinarybladder    
    Visualeye    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • 18 C2H2 zinc fingers which were organized in two clusters
    • HOMOLOGY
    Homologene
    FAMILY
  • zinc fingers protein family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • could activate a reporter luciferase gene driven by this DNA sequence
  • zinc finger protein having a novel binding specificity and transcription regulatory activity
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS