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FLASH GENE
Symbol ZNF621 contributors: npt - updated : 18-05-2009
HGNC name zinc finger protein 621
HGNC id 24787
Location 3p22.1      Physical location : 40.566.375 - 40.581.043
Synonym symbol(s) FLJ45246, DKFZp686B11107, FLJ23786, MGC126668
DNA
TYPE functioning gene
STRUCTURE 14.67 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text two variants encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 8051 49 439 - kimura (2006)
5 - 8287 49 439 - Kimura (2006)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestivestomach   moderately
Nervousbrain   moderately
Reproductivefemale systemuterus  moderately
 female systemovary  moderately
 male systemprostate  highly
Skin/Tegumentskin   highly
Urinarykidney   moderately
Visualeye   moderately
cell lineage
cell lines
fluid/secretion blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • C2H2-type zinc fingers
  • KRAB domain
  • HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • playing a role in the regulation of transcription, DNA-dependent
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS