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FLASH GENE
Symbol ZNF57 contributors: mct - updated : 05-06-2013
HGNC name zinc finger protein 57
HGNC id 13125
Location 19p13.3      Physical location : 2.900.895 - 2.918.467
Synonym name zinc finger protein 424
Synonym symbol(s) ZNF424
DNA
TYPE functioning gene
STRUCTURE 17.58 kb     4 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 2016 64 555 - 2010 20356463
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • C2H2-type zinc fingers
  • KRAB domain
    • HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
    • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    text localizes mostly in the nucleus
    basic FUNCTION
  • involved in the regulation of transcription, DNA-dependent
  • may act as a transcriptional repressor that suppresses NFATC1 and CDKN1A pathway to mediate cellular functions
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS