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FLASH GENE
Symbol ZNF536 contributors: SGE/npt - updated : 14-08-2009
HGNC name zinc finger protein 536
HGNC id 29025
Location 19q12      Physical location : 30.863.327 - 31.048.965
Synonym symbol(s) KIAA0390
DNA
TYPE functioning gene
STRUCTURE 185.64 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 4935 - 1300 - -
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainforebraincerebral cortex  
 brainlimbic systemhippocampus  
 brain   highly
 braindiencephalonhypothalamus  
 ganglia    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • nine C2H2-type zinc fingers
  • HOMOLOGY
    interspecies homolog to murine Zfp536 (88.8pc)
    homolog to rattus Znf536 (88.8pc)
    Homologene
    FAMILY
  • kruŽppel C2H2-type zinc finger protein family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in transcription
  • negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcription (Qin 2009)
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS