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FLASH GENE
Symbol ZNF486 contributors: npt - updated : 29-05-2009
HGNC name zinc finger protein 486
HGNC id 20807
Location 19p12      Physical location : 20.278.082 - 20.308.984
Synonym name KRAB domain only 2
Synonym symbol(s) MGC2396, KRBO2
DNA
TYPE functioning gene
STRUCTURE 30.90 kb     4 Exon(s)
MAPPING cloned Y linked N status provisional
Physical map
TM6SF2 19p13.3-p12 transmembrane 6 superfamily member 2 SF4 19p13 splicing factor 4 KIAA0892 19p13.11 KIAA0892 p66alpha 19p13.11 p66 alpha CLIP-2 19p13.11 cartilage intermediate layer protein-like protein 2 SSTK 19p13.11 serine/threonine protein kinase SSTK GRIM19 19p13.2 serine/threonine protein kinase SSTK FLJ44968 19p13.11 FLJ44968 protein PBX4 19p12 pre-B-cell leukemia transcription factor 4 EDG4 19p12 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4 GMIP 19p11-p12 Gem-interacting protein CGI-152 HZF12 ZNF14 19p13.3-p13.2 zinc finger protein 14 (KOX 6) LOC390898 19 similar to sorting nexin associated golgi protein 1 MGC39821 19p13.11 hypothetical protein MGC39821 ZNF506 19p13.11 zinc finger protein 506 LOC390899 19 similar to hypothetical protein FLJ12488 ZNF253 19p13.1 zinc finger protein 253 ZNF505 19p13.11 zinc finger protein 505 LOC91120 19p13.11 hypothetical ZNF-like protein ZNF90 19p13.1-p12 zinc finger protein 90 (HTF9) LOC388519 19 similar to 40S ribosomal protein S16 ZNF486 19p13.11 zinc finger protein 486 LOC284441 19p13.11 similar to actin-related protein 2 LOC390900 19 similar to hypothetical protein FLJ12488 LOC388520 19 hypothetical gene supported by AK126842 LOC163233 19p13.11 similar to Zinc finger protein 93 (Zinc finger protein HTF34) LOC390901 19 similar to Zinc finger protein 431 LOC199777 19p13.11 similar to DNA-binding protein; zinc finger protein 253 LOC390902 19 similar to Zinc finger protein 93 (Zinc finger protein HTF34) LOC390903 19 similar to Zinc finger protein 93 (Zinc finger protein HTF34) LOC342991 19p13.11 similar to hypothetical protein FLJ12488 ZNF85 19p12 zinc finger protein 85 (HPF4, HTF1) LOC390904 19 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) ZNF430 19p12 zinc finger protein 430
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 1522 53.5 463 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one KRAB domain
  • HOMOLOGY
    Homologene
    FAMILY
  • Krüppel C2H2 type zinc finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may have a role in the regulation of transcription
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS