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FLASH GENE
Symbol ZNF449 contributors: mct - updated : 19-06-2007
HGNC name zinc finger protein 449
HGNC id 21039
Location Xq26.3      Physical location : 134.478.695 - 134.497.337
Synonym name zinc finger and SCAN domain-containing protein 19
Synonym symbol(s) ZSCAN19, FLJ23614
DNA
TYPE functioning gene
STRUCTURE 18.00 kb     5 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouth   highly
Reproductivefemale systemplacenta  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose  highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a leucine-rich region at the N-terminus (LER or SCAN domain)
  • seven C2H2-type zinc fingers domains at the C terminus, 7 C(2)H(2) (Cys2-His2) zinc-finger motifs
    • HOMOLOGY
    interspecies ortholog to murine Zfp449 (88 pc)
    Homologene
    FAMILY krueppel C2H2-type zinc-finger protein family
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • involved in the regulation of transcription, DNA-dependent
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS