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FLASH GENE
Symbol ZNF43 contributors: npt - updated : 29-12-2005
HGNC name zinc finger protein 43
HGNC id 13109
Location 19p13.1-p12      Physical location : 21.987.752 - 22.018.970
Synonym name
  • zinc finger protein 43 (HTF6)
  • zinc finger protein 39
  • zinc finger protein KOX27
  • Synonym symbol(s) HTF6, KOX27, ZNF39L1, ARK1, AURKA, AURORA2, BTAK, DKFZp686L1854
    DNA
    TYPE functioning gene
    STRUCTURE 31.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    LOC91120 19p13.11 hypothetical ZNF-like protein ZNF90 19p13.1-p12 zinc finger protein 90 (HTF9) LOC388519 19 similar to 40S ribosomal protein S16 ZNF486 19p13.11 zinc finger protein 486 LOC284441 19p13.11 similar to actin-related protein 2 LOC390900 19 similar to hypothetical protein FLJ12488 LOC388520 19 hypothetical gene supported by AK126842 LOC163233 19p13.11 similar to Zinc finger protein 93 (Zinc finger protein HTF34) LOC390901 19 similar to Zinc finger protein 431 LOC199777 19p13.11 similar to DNA-binding protein; zinc finger protein 253 LOC390902 19 similar to Zinc finger protein 93 (Zinc finger protein HTF34) LOC390903 19 similar to Zinc finger protein 93 (Zinc finger protein HTF34) LOC342991 19p13.11 similar to hypothetical protein FLJ12488 ZNF85 19p12 zinc finger protein 85 (HPF4, HTF1) LOC390904 19 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) ZNF430 19p12 zinc finger protein 430 ZNF431 19p12 zinc finger protein 431 LOC148203 19p13.11 hypothetical protein LOC148203 LOC388521 19 similar to hypothetical protein LOC390905 19 similar to hypothetical protein LOC163227 LOC115648 19p13.11 similar to hypothetical protein FLJ13659 ZNF493 19p13.11 zinc finger protein 493 LOC388522 19 similar to Zinc finger protein 429 LOC163227 ZNF43 19p13.1-p12 zinc finger protein 43 (HTF6) ZNF208 19p12 zinc finger protein 208 ZNF257 19q13 zinc finger protein 257 LOC253272 19p13.11 ring finger protein 134 pseudogene LOC163223 19p13.11 similar to Zinc finger protein 208 LOC342994 19p13.11 similar to ribosomal protein L34; 60S ribosomal protein L34 LOC148198 19p13.11 similar to Zinc finger protein 492 LOC342999 19p13.11 similar to ZNF43 protein LOC374890 19p13.11 hypothetical gene supported by BC030765 ZNF492 19p13.11 zinc finger protein 492 LOC390906 19 similar to Zinc finger protein 492 LOC126502 19p13.11 similar to zinc finger protein 91 (HPF7, HTF10) LOC388523 19 similar to Zinc finger protein 208 LOC126506 19p13.11 sorting nexin 6 pseudogene ZNF91 19p12 zinc finger protein 91 (HPF7, HTF10)
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    4 - 5225 - 809 - -
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Lymphoid/ImmuneT cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a KRAB (Krüppel associated box) at the N terminus
  • 22 tandemly arranged zinc finger motifs of the C2H2 type at the C terminus
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • KRAB subfamily
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • potential transcriptional repressor
  • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS