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FLASH GENE
Symbol ZNF385B contributors: mct/npt - updated : 11-02-2009
HGNC name zinc finger protein 385B
HGNC id 26332
Location 2q31.2      Physical location : 180.306.719 - 180.726.232
Synonym name
  • hypothetical protein FLJ3950
  • zinc finger protein 533
  • Synonym symbol(s) FLJ25270, ZNF533
    DNA
    TYPE functioning gene
    STRUCTURE 419.35 kb     10 Exon(s)
    MAPPING cloned Y linked N status provisional
    Map cen - D2S324 - D2S250 - ZNF385B - D2S2261 - D2S384 - qter
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 2793 - 395 - Gerhard (2004)
    - - 2653 - 369 - Gerhard (2004)
    10 - 3320 50 471 - Gerhard (2004)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • four U1-type zinc fingers
  • HOMOLOGY
    interspecies ortholog to murine Zfp533
    Homologene
    FAMILY
  • C2H2-type zinc fingers present in matrin family
  • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be playing a role in RNA maturation and/or stability (Monfort 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional   deletion    
    in mental retardation
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS