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FLASH GENE
Symbol ZNF354C contributors: npt - updated : 16-04-2009
HGNC name zinc finger protein 354C
HGNC id 16736
Location 5q35.3      Physical location : 178.487.606 - 178.507.689
Synonym name
  • KRAB-zinc finger protein synten
  • kidney, ischemia, and developmentally-regulated protein 3
    • Synonym symbol(s) KID3
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text clustered with ZNF354A and ZNF354B
    STRUCTURE 20.08 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 2390 64.7 554 - Gao (2004)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Digestiveintestinesmall intestine   
    Nervousbrain   highly
    Respiratorylung    
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period embryo
    Text brain
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a KRAB domain
  • Krüppel-associated box at the N terminus
  • several zinc finger motifs of the C2H2 Krüppel type at the C terminus
    • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
    • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • potential transcription regulator
  • may be involved in the early stages of nephrogenesis
    • CELLULAR PROCESS nucleotide, transcription, regulation
    cell organization/biogenesis
    PHYSIOLOGICAL PROCESS development
    text nephrogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS